The Arizona Cardinals (2-8) travel to California this weekend to take on the Los Angeles Chargers (7-3). Kickoff is set for 4:05 PM EST on November 25th at the StubHub Center and the game will be broadcast on FOX.

Oddsmakers opened this game up with the Chargers listed as 11.5-point home favorites. That line has shifted by half a point after early betting, as Los Angeles is currently available at -12. The total for this matchup is 45 points. Click here for a full look at the Week 12 NFL odds and for more links to our individual game previews.

Chargers vs Cardinals Vegas Odds & Game Preview

Arizona dropped to 2-8 on the season last weekend after dropping a close 23-21 decision to the Oakland Raiders. The Cardinals had several chances to win the game outright but committed several costly turnovers including two interceptions by rookie QB Josh Rosen. However, Rosen did also throw three touchdowns passes in the loss, which was a positive sign for the coaching staff. RB David Johnson continued his resurgence on the ground, rushing for a season-high 137 yards against a bad Raiders run defense. The only other noteworthy offensive performance in Week 11 was that of WR Christian Kirk, who turned three receptions into 77 yards and a touchdown. Overall, Arizona is currently averaging just 14.5 points per game (31st overall) on 240.8 total yards of offense.

The Cardinals have been pretty mediocre defensively through their first ten games, as opponents are currently averaging 24.8 points per game (17th overall) on 359.7 yards of total offense. They have really had a rough time on the ground, getting torched for 141.5 rushing yards per game (29th overall).

Los Angeles saw their six-game winning streak come to an end last weekend, blowing a 12-point lead before eventually losing a tough 23-22 decision to Denver. It was especially disappointing that the defeat came at the hands of a hated division rival, as the Broncos desperately needed the win to give themselves any shot in the tough AFC West. In any event, the Chargers have certainly been playing well for the last month and a half after a slow 1-2 start to the season in September. QB Philip Rivers is enjoying another fantastic campaign, throwing for almost 3,000 yards in just ten games while finding the end zone at least twice per contest over 11 straight starts. He has certainly had a lot of help from RB Melvin Gordon III, who has racked up over 1,100 total yards and eleven total touchdowns (seven rushing, four receiving). As a whole, Los Angeles is currently averaging 26.2 points per game (9th overall) on 400.8 total yards of offense.

The Chargers have been pretty good on the other side of the ball so far this season, holding opponents to an average of 20.9 points per game (7th overall) on 353.4 yards of total offense. However, they have been mediocre at best against the run through ten games, surrendering an average of 112.1 yards per contest (18th overall).

Free NFL Betting Prediction: Arizona +12

Let me start this off by stating that I don’t think that the Cardinals have a very good chance at pulling off the upset on the road this weekend. Josh Rosen has been highly inconsistent through his first full year as a pro and Los Angeles has certainly shown that they have an above average secondary. However, the awakening of David Johnson has really sparked the Arizona offense as of late, as they have stayed within 12 points of both Minnesota and Kansas City. If Rosen avoids throwing 2-3 interceptions in this matchup, there is no reason why the Cards can’t stay within 7-10 points of the home favorite in this spot.

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The Chargers are just 1-6 ATS over their last seven home games as a double-digit favorite. They are also only 2-7 ATS in their last nine games as a double-digit favorite overall. Arizona is a solid 9-3 ATS over their last 12 games as a double-digit underdog. The underdog is also 5-2 ATS over the last seven meetings between these two teams.

It is also important to note that home field advantage hasn’t really meant all that much in this particular matchup, as the home team is just 1-6 ATS over the last seven games between the Chargers and Cardinals. Los Angeles certainly isn’t a better team than Kansas City, and Arizona only lost that game by 12 points despite getting completely shut out in the second half. I think this one stays close throughout, so I’m going to take the free 12 points and take a stab with the road underdog.