The Duke Blue Devils (7-3) travel to Death Valley this weekend for an ACC battle with the #2 overall Clemson Tigers (10-0). Kickoff is set for 7:00 PM EST at the Clemson Memorial Stadium and the game will be broadcast on ESPN.

Taking a look at the Week 12 college football odds, Clemson opened as a 27.5-point home favorite earlier this week. That line has remained the same after early betting, as the Tigers are currently listed at -27.5. The total for the game is sitting at 56.5 points.

Vegas Betting Preview & Game Odds: Clemson vs Duke

Duke won their second game in a row last weekend to improve to 7-3 overall on the season. The Blue Devils put on a show offensively for a home crowd, as they topped North Carolina 42-35 at Wallace Wade Stadium. QB Daniel Jones had a record-breaking day, throwing for 361 yards and three touchdowns while also adding 186 yards and a touchdown on the ground. In all, his 547 yards of total offense broke the all-time Duke record. Jones has now passed for 1,948 yards and 16 touchdowns in ten games -including eight over his last four starts. RB Deon Jackson also had a quality game against the Tar Heels, rushing for 78 yards and a touchdown. As a whole, the offense is currently averaging 31.5 points per game on 419.8 total yards. They have really been able to move the ball well on the ground, rushing for an average of 174.2 rushing yards per game.

The Blue Devils have been above average on the other side of the ball, allowing opponents to score 23.5 points per game on 405.7 yards of total offense. However, they have really struggled to defend against the run, giving up 212.0 yards per game on the ground (108th overall).

Clemson stayed perfect last weekend, beating #17 overall Boston College 27-7 to improve to 10-0 on the year. The Tigers jumped out to an early 10-7 lead and never looked back, shutting out the Eagles in the second half while adding two more touchdowns of their own. The victory cemented their fourth consecutive trip to the ACC Championship game, while also propelling them one step closer to the College Football Playoff. QB Trevor Lawrence played well, throwing for 295 yards and a touchdown. He has now passed for 1,844 yards and 19 touchdowns in just ten games. Clemson has also been fantastic on the ground so far this season, averaging 251.7 rushing yards per game (12th overall). Overall, the offense is currently averaging 45.7 points per game (5th overall).

On the other side of the ball, the Tigers are currently giving up just 12.7 points per game (1st overall) on 253.6 yards of total offense. They have really looked fantastic against the rush through ten games, allowing opponents to average only 82.3 yards on the ground per game on the ground (3rd overall).

NCAA Football Betting Predictions & Free Pick: Duke +27.5

Fans of defense will certainly not want to miss this matchup here in Week 12, as both teams have been quite strong in terms of total points allowed per game. There is no doubt in my mind about who will win outright in this particular spot, as Clemson has been a juggernaut all season long and can’t afford to have a letdown so close to reaching the College Football Playoff yet again this year. However, the current line is a little bit steep for my liking. Duke has also played well so far this season, especially on the road where they are currently 4-1. They also have a quarterback who is more than capable of single-handedly keeping them in a game, as Jones is currently ranked as a Top-25 prospect in the upcoming 2019 NFL Draft.

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Clemson is only 2-4 ATS over their last six games at home. The Blue Devils are a very impressive 6-1 ATS in their last seven road games. They are also 5-1 ATS over their last six road games against teams with a winning home record and 10-3 straight up in their last 13 games overall.

While the Tigers have shown that they are capable of blowing teams out this season, they seem to have struggled a bit against dual-threat quarterbacks. Clemson really had a tough time against both Syracuse and Texas A&M, as both games ended up being much closer than expected. I think that Daniel Jones should find a way to keep his team in the game for four straight quarters, so I’m going to take all the free points and roll with the road underdog to grind out a cover – give me the Blue Devils.