The Virginia Cavaliers are set to host the Indiana Hoosiers in a ACC/Big Ten non-conference clash in Week 2. Kickoff set for 3:30 EST at Scott Stadium in Charlottesville and will be televised on ESPNU.

Taking a look at the Week 2 betting lines, oddsmakers have the Hoosiers listed as a 3-point road favorite with the total at 56 points.

Indiana vs Virginia Vegas Betting Odds & Free Game Preview

Indiana looked like they might pull off one of the biggest upsets of the season in Week 1. The Hoosiers had a 21-20 lead with less than 5 minutes to play in the 3rd quarter. That’s when things went south, as the Buckeyes scored 28 unanswered to win 49-21. Indiana backers were left scratching their heads, as Ohio State also covered as a 20.5-point favorite.

If you watched that game, you know the Hoosiers played better than the final score would indicate. They simply wore out of gas against a far superior team. It was an impressive debut for new head coach Tom Allen against a Top 5 opponent. Both sides of the ball showed flashes of excellence. Senior QB Richard Lagow threw for 410 yards and 3 scores, while the defense held OSU to just 13 first half points.

Virginia opened with a 28-10 win at home over William & Mary. They came up well short of covering as a 25.5-point favorite. On the bright side, it was a lot better than last year’s 20-37 defeat to Richmond in their opener at home as a 13-point favorite.

The offense was led by senior QB Kurt Benkert and his 262 yards and 3 scores through the air. As for the running game, the Cavaliers managed just 92 yards on 32 attempts against a FCS opponent. It also appears Virginia still has a major problem in the kicking game, forcing them to go for it on 4th down when others would take the 3-points.

Free College Football Betting Prediction Against the Spread: Virginia +3

This game is getting a lot of action early, as the public is jumping all over Indiana as a short road favorite. They see how well they played against a Top 5 program and see no reason why they won’t have their way with Virginia. More times than not, when something looks this obvious to the public, I’m going to lean the other way.

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A big thing to keep in mind is that’s not the first time the Hoosiers played the Buckeyes tough. In fact, they were only down 17-24 in the 3rd quarter last year a No. 2 Ohio State before losing 17-38. The year before they lost by a final of just 27-34 at home to a Buckeyes team that was ranked No. 1.

To play so well for such a big chunk of the game and end up losing by 28-points is demoralizing for a team. I wouldn’t be the least bit surprised to see this team come out flat against a Virginia team that didn’t play well in their opener.

This is also a Indiana program that routinely struggles on the road. Last year they had 2 road wins, but they were a 34-13 victory at FIU and 33-27 win at Rutgers.

It’s hard to get excited about Virginia’s offensive performance against William & Mary, but Benkert is an experienced signal caller, who got back his top two targets from last year. I think he’s going to be able to keep Virginia’s offense on the field and put some points on the boar.

Indiana’s passing attack wasn’t the same in the 2nd half after OSU made adjustments. Expect Bronco Mendenhall and his staff to take note of what the Buckeyes did and use that in their gameplan. Keep in mind that Indiana featured zero threat of a running game against Ohio State, totaling 17 yards on 26 attempts. It’s really hard to win on the road when you struggle to pick up yards on the ground.