The Buffalo Bulls (1-0) travel to University Park this weekend for a road matchup against the Penn State Nittany Lions (1-0). Kickoff is set for 7:30 PM EST on Saturday, September 7th at Beaver Stadium and the game will be televised nationally on FOX.

Taking a look at the Week 2 college football odds,  Penn State opened as a 24-point home favorite earlier this week. That line has skyrocketed by over four points after early betting, as the Nittany Lions are currently listed at -28.5. The total for the game is sitting at 56 points.

Vegas Betting Preview & Game Odds: Penn State vs Buffalo

Buffalo looked very impressive in Week 1, beating Robert Morris 38-10 at home to move to 1-0. The Bulls jumped out to a quick 21-7 lead in the first quarter and never looked back, only giving up a field goal the rest of the way. QB Matt Myers didn’t have to do much through the air, as he was just 5/10 for 69 yards through the air. However, he did also make two touchdown passes and find the end zone on one of his four rushing attempts as well. RB Jaret Patterson also had a good game on the ground, rushing for 90 yards and a touchdown on 12 carries. Zac Lefebvre led the way for the receiving corps, catching two passes for 43 yards and two touchdowns. Overall, the Buffalo offense gained over 300 total yards and scored five touchdowns against a sub-par Colonials defense.

The Bulls also looked solid on defense in Week 1, although it’s probably still a bit early to get overly excited considering the caliber of the opposing offense. Still, Buffalo managed to limit Robert Morris to less than 100 yards through the air and only gave up one touchdown total over four quarters of action.

Penn State absolutely destroyed Idaho last weekend, crushing the Vandals 79-7 at home. The Nittany Lions gained more than 650 total yards of offense and scored ten touchdowns in what clearly was an offensive onslaught of epic proportions. QB Sean Clifford was 14/23 for 280 yards and two touchdowns while Noah Cain and Journey Brown each scored two touchdowns of their own on the ground. WR KJ Hamler also had a two touchdown performance, catching four passes for 115 receiving yards to lead the Penn State in receiving. It certainly was a team effort offensively, as six different starters had found the end zone by the end of the fourth quarter.

The Nittany Lions were also quite impressive on defense in Week 1, holding Idaho to just seven points. Of course, they certainly didn’t face that much of a test as the Vandals are far from an offensively gifted team. Penn State gave up less than 150 total yards and didn’t allow starting Idaho QB Mason Petrino to eclipse the 100-yard passing mark either.

NCAA Football Betting Predictions & Free Pick: Penn State -28.5

I’m not sure just how much weight we can put on either of these two teams impressive performances in Week 1 once the quality of their opposition is taken into account. Penn State won by a ridiculous 70+ points while Buffalo also ran up the score against George Mason program. This line has increased dramatically since it opened at -24, and I’m not sure it’s necessarily done climbing yet. The Nittany Lions look to be the real deal on both sides of the ball, which makes me pretty bearish on Buffalo’s chances of success on the road here in Week 2.

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I also don’t have a good read on how freshman QB Matt Myers will perform in his first big test in a hostile environment on national television. Myers didn’t have to do much last week against the Colonials, as the game was basically out of reach by halftime. He certainly isn’t battle-tested and there is no way anything other than a “wait and see” approach is optimal with such a wildcard leading the offense. The Nittany Lions are the more experienced team on both sides of the ball and will be extremely motivated to keep their early season momentum rolling this week at Beaver Stadium. I’m going to jump on this line before it continues to move higher before kickoff on Saturday evening – give me Penn State to cover at home.