The Texas Tech Red Raiders (2-2) host the #21 overall Oklahoma State Cowboys (4-1) for a pivotal BIG 12 matchup from Lubbock.  Kickoff is set for 12:00 PM EST on Saturday, October 5th at Jones AT&T Stadium and the game will be televised on FS1.

Taking a look at the Week 6 college football odds, OSU opened as a 8-point road favorite earlier this week. That spread has increased by two full points after early betting, as the Cowboys are currently listed at -10. The total for the game is sitting at 63.5 points.

Vegas Betting Preview & Game Odds: Texas Tech vs Oklahoma State

Oklahoma State lost their first game of the season last weekend, falling 36-30 on the road against #11 overall Texas. The Cowboys trailed by a single point after the first two quarters and couldn’t find a way to come out on top, getting outscored 15-10 by the Longhorns over the final 30 minutes. QB Spencer Sanders had a rough outing through the air, passing for 268 yards and getting picked off twice. However, Sanders did chip in 108 yards and a touchdown over 18 rushing attempts. RB Chuba Hubbard continued to be a monster on the ground, racking up 121 yards and two touchdowns on a game-high 37 carries. Tylan Wallace led the way for the receiving corps, making five catches for 83 yards. As a whole, OSU  generated just under 500 total yards of offense and scored three touchdowns despite coming up just short on the scoreboard.

The Cowboys defense didn’t have a great outing against Texas, giving up over 500 total yards of offense and five touchdowns. Oklahoma State couldn’t find a way to slow down Longhorns QB Sam Ehlinger, who had four touchdown passes on the evening.

Texas Tech dropped back to .500 overall on the season last weekend after getting crushed 55-16 on the road against Oklahoma. The Red Raiders gave up 34 points in the first half alone, as they trailed by 3+ touchdowns at the half in a game that was basically over midway through the third quarter. QB Jett Duffey had a rough outing, going only 11/20 for 120 yards through the air. RB SaRodorick Thompson led the way on the ground, rushing for 96 yards on 13 carries. None of the Texas Tech receiving corps could really get anything going all game long, as Dalton Rigdon posted the most receiving yards despite only catching two passes for 37 total yards. Overall, the offense gained just over 300 total yards and scored just a single touchdown against a very tough Sooners defense.

The Red Raiders also really struggled on the other side of the ball against Oklahoma, allowing the Sooners to rack up well over 600 total yards of offense and score seven touchdowns. Texas Tech was especially poor defending against the pass, getting torched for 443 yards and three touchdowns through the air.

NCAA Football Betting Predictions & Free Pick: Oklahoma State -10

The Cowboys could easily be 5-0 overall right now, as they had several opportunities to pull out a tough road victory against Texas last Saturday. However, they have still looked extremely strong over the first five weeks of the season, scoring an average of well over 40 points per game. While Texas Tech has also looked fairly solid at times this year, the Red Raiders have really struggled over their last few outings, getting outscored 83-30. Of course, one of those losses came against a powerhouse Oklahoma program, but the other was a double-digit defeat against a mediocre Arizona Wildcats squad. As long as this spread stays below 10.5 points, I think the Cowboys offer the best value in this important BIG 12 matchup.

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Oklahoma State has also owned this rivalry as of late, going an extremely impressive 9-1 straight up over their last ten meetings with the Red Raiders. The Cowboys are also a perfect 6-0 against the spread in their last six games overall and 4-1 ATS over their last five road games. On the other side, Texas Tech is just 1-5-1 ATS in their last seven games overall. They are also a brutal 0-5 straight up over their last five games at home against the Cowboys. OSU is clearly the better team on both sides of the ball and should come out highly motivated after such a tough road loss in Week 5. I’ll lay the 10 points and side with the favorite in this matchup – give me Oklahoma State!