The #21 overall Virginia Cavaliers (3-0) host the Old Dominion Monarchs (1-1) this weekend in Charlottesville. Kickoff is set for 7:00 PM EST on Saturday, September 21st at Scott Stadium and the game will be televised on ESPN2.

Taking a look at the Week 4 college football odds, Virginia opened as a huge 30-point home favorite earlier this week. That line has shifted by half a point after early betting, as the Cavaliers are currently listed at -30.5. The total for the game is sitting at 52.5 points.

Vegas Betting Preview & Game Odds: Virginia vs Old Dominion

Old Dominion had Week 3 off after losing 31-17 on the road to Virginia Tech at the beginning of September. The Monarchs trailed 17-3 at the half and never fully recovered, allowing the Hokies to score two more touchdowns down the stretch to put the game out of reach. QB Stone Smartt didn’t have a good game through the air, going just 16/30 for 122 passing yards. However, Smartt did rack up 48 rushing yards and score two touchdowns on the ground. RB Elijah Davis also had a solid performance in the running game, averaging 7.4 yards per carry on 11 touches. WR Steven Williams led the way for the receiving corps, making only three catches for 36 yards. Overall, Old Dominion gained more than 300 total yards of offense and scored two touchdowns against an above average Virginia Tech defense.

The Monarchs defense didn’t have their best outing against Virginia Tech, giving up almost 400 yards of total offense and four touchdowns. However, Old Dominion did do a pretty good job against the Hokies ground attack as no running back gained more than 64 rushing yards or averaged more than 4.2 yards per carry.

Virginia moved to 3-0 on the season overall last weekend after a thrilling second half comeback at home against Florida State. The Cavaliers trailed 14-10 at halftime before exploding for 21 points in the fourth quarter en route to a 31-24 victory. QB Bryce Perkins struggled with turnovers in the passing game, going 30/40 for 295 yards and a touchdown but also throwing two costly interceptions. RB Wayne Taulapapa led the way on the ground for Virginia, rushing for 53 yards and three touchdowns. The receiving duo of Terrell Jana and Joe Reed also had a solid performance, combining for 15 receptions, 168 yards, and a touchdown. As a whole, the offense racked up more than 400 total yards and scored four touchdowns against the Seminoles defense.

The Cavaliers defense had an average game against Florida State, giving up well over 300 total yards of offense and three touchdowns. Virginia really got exposed through the air, as Seminoles QB James Blackman threw for 234 yards and three touchdowns.

NCAA Football Betting Predictions & Free Pick: Virginia -30.5

This line actually looks very accurate to me, so I certainly don’t feel that strongly about either side of this matchup. However, Old Dominion really struggles to move the ball through the air on offense, which doesn’t bode well for the Monarchs against a very tough Cavaliers run defense. Virginia also beat Pitt by 16 points back in Week 1 before crushing William & Mary by 35 points in Week 2. Their offense should be able to put up a lot of points against an Old Dominion defense that just have up 31 points to the Hokies a couple of weeks ago.

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The Cavs have performed quite well against the spread as of late, going 3-0-1 ATS over their last four games. Virginia is also a very impressive 5-1 ATS in their last six non-conference games. Bryce Perkins didn’t have his best outing in Week 3 against Florida State but should rebound here at home against a suspect Monarchs defense. The Cavaliers also have been extremely solid on the other side of the ball, holding their opponents to an average of 18.3 points per game. Again, while I will likely stay away from this particular spot entirely, I’d rather take a shot with the Top 25 ranked Virginia team playing at home on Saturday. Give me the Cavaliers!