We are just a few days away from the start of another NFL season. I’ve put together a full betting schedule for Week 1 NFL with game odds, start times and TV listings.

Over the next few days our staff will be previewing a number of the games. Links to the previous will be added to the table below, so be sure to check back often.

Week 1 NFL Vegas Game Lines:  Point Spreads & Betting Totals

The 2019 season will officially get underway on Thursday, September 5th. It’s the 100th anniversary season, so they decided to change things up.

In years past the defending champ would play at home in the opener. This season it’s a classic NFC North rivalry between the Green Bay Packers and Chicago Bears.

The New England Patriots will instead play their first games as defending champs on Sunday Night Football, as they are set to host the Pittsburgh Steelers.

The rest of Sunday’s card leaves a lot to be desired, as there’s just not a lot of great matchups on paper. There are a number of division games that will draw attention, but I would have to think Falcons @ Vikings, Chiefs @ Jaguars, Rams @ Panthers and [email protected] Browns are the best of the bunch.

Week 1 will conclude with a Monday Night Football double-header. First it will be the Texans @ Saints, followed by the Broncos @ Raiders.

Two teams are near double-digit favorites in Week 1. The Seahawks are 9.5-point home favorite of the Bengals and the eagles are 9.5-point home favorite against the Redskins.

For even more expert advice, be sure to check out our free NFL picks page.

Week 1 NFL Odds

Thursday, September 5, 2019

Time (TV)MatchupSpreadTotalPreview
8:30pm (NBC)Green Bay Packers
Chicago Bears
+3
-3
46.5 Preview

Sunday, September 08, 2019

Time (TV)MatchupSpreadTotalPreview
1:00pm (FOX)Atlanta Falcons
Minnesota Vikings
+4
-4
47.5 Preview
1:00pm (FOX)Washington Redskins
Philadelphia Eagles
+9.5
-9.5
46 Preview
1:00pm (CBS)Buffalo Bills
New York Jets
+3
-3
40 Preview
1:00pm (CBS)Baltimore Ravens
Miami Dolphins
-6.5
+6.5
37.5 Preview
1:00pm (CBS)Kansas City Chiefs
Jacksonville Jaguars
-3.5
+3.5
52 Preview
1:00pm (CBS)Tennessee Titans
Cleveland Browns
+5.5
-5.5
45.5 Preview
1:00pm (FOX)Los Angeles Rams
Carolina Panthers
-3
+3
50.5 Preview
4:05pm (CBS)Cincinnati Bengals
Seattle Seahawks
+9.5
-9.5
44 Preview
4:05pm (CBS)Indianapolis Colts
Los Angeles Chargers
+6.5
-6.5
43.5 Preview
4:25pm (FOX)Detroit Lions
Arizona Cardinals
-2.5
+2.5
47 Preview
4:25pm (FOX)San Francisco 49ers
Tampa Bay Buccaneers
+1
-1
50 Preview
4:25pm (FOX)New York Giants
Dallas Cowboys
+7
-7
45.5 Preview
8:20pm (NBC)Pittsburgh Steelers
New England Patriots
+5.5
-5.5
51 Preview

Monday, September 9, 2019

Time (TV)MatchupSpreadTotalPreview
7:10pm (ESPN)Houston Texans
New Orleans Saints
+7
-7
53.5 Preview
10:20pm (ESPN)Denver Broncos
Oakland Raiders
PK
PK
43 Preview

Check Out Each of the Weekly NFL Odds & Betting Lines: