The 2017-18 NFL season will officially get underway on Thursday, September 7th with the New England Patriots hosting the Kansas City Chiefs on NBC. Action continues with a loaded card on Sunday and will wrap up with the annual Week 1 double-header for Monday Night Football.

I’ve put together a full schedule and list of betting odds for opening week below. Keep in mind that the lines for these games have been up for quite some time, as they are first released in late spring. I’ve included those opening odds, as well as the current lines for the spread.

Week 1 NFL Vegas Game Lines:  Point Spreads & Betting Totals

Leading up to the action, our experts on staff will be giving out free betting leans on either the spread or total of each game. Similar to what was done for week 1 college football. Be sure to check back often, as links will be added as the articles are completed each day.

The Chiefs/Patriots is one of the best matchups in Week 1. Two other contests that figure to get a ton of attention is Sunday’s late afternoon showdown that has Seattle at Green Bay and Sunday Night Football’s NFC East clash between the Cowboys and Giants.

Other notable games on tap for Sunday include the Eagles/Redskins, Ravens/Bengals, Raiders/Titans and Cardinals/Lions. Week 1 will conclude with the Saints at Vikings (AP returns home), followed by an AFC West Rivalry with Chargers at Broncos.

For even more expert advice, be sure to check out our free NFL picks page.

Week 1 NFL Odds

Thursday, September 7, 2017

Time (TV)MatchupOpenCurrentTotalPreview
8:30pm (NBC)Kansas City Chiefs
New England Patriots
+8
-8
+8.5
-8.5
48.5 Preview

Sunday, September 10, 2017

Time (TV)MatchupOpenCurrentTotalPreview
1:00pm (FOX)Tampa Bay Buccaneers
Miami Dolphins
+2
-2
PPD
PPD
PPD Preview
1:00pm (CBS)New York Jets
Buffalo Bills
+6.5
-6.5
+9.5
-9.5
40 Preview
1:00pm (CBS)Jacksonville Jaguars
Houston Texans
+4.5
-4.5
+5.5
-5.5
39.5 Preview
1:00pm (FOX)Atlanta Falcons
Chicago Bears
-6
+6
-7
+7
49 Preview
1:00pm (FOX)Philadelphia Eagles
Washington Redskins
+2.5
-2.5
-1
+1
47.5 Preview
1:00pm (FOX)Arizona Cardinals
Detroit Lions
+2.5
-2.5
-2
+2
48 Preview
1:00pm (CBS)Oakland Raiders
Tennessee Titans
-1
+1
+2
-2
50.5 Preview
1:00pm (CBS)Baltimore Ravens
Cincinnati Bengals
+1
-1
+3
-3
42.5 Preview
1:00pm (CBS)Pittsburgh Steelers
Cleveland Browns
-9.5
+9.5
-9
+9
46.5 Preview
4:05pm (CBS)Indianapolis Colts
Los Angeles Rams
-3.5
+3.5
+3.5
-3.5
41.5 Preview
4:25pm (FOX)Seattle Seahawks
Green Bay Packers
+3
-3
+3
-3
51 Preview
4:25pm (FOX)Carolina Panthers
San Francisco 49ers
-4
+4
-5.5
+5.5
48 Preview
8:30pm (NBC)New York Giants
Dallas Cowboys
+6
-6
+4
-4
47.5 Preview

Monday, September 11, 2017

Time (TV)MatchupOpenCurrentTotalPreview
7:10pm (ESPN)New Orleans Saints
Minnesota Vikings
+3.5
-3.5
+3.5
-3.5
48 Preview
10:20pm (ESPN)Los Angeles Chargers
Denver Broncos
+4
-4
+3.5
-3.5
43.5 Preview

Check Out Each of the Weekly NFL Odds & Betting Lines: