We are just a few days away from the start of another NFL season. I’ve put together a full betting schedule for Week 1 NFL with game odds, start times and TV listings.

Over the next few days our staff will be previewing a number of the games. Links to the previous will be added to the table below, so be sure to check back often.

Week 1 NFL Vegas Game Lines:  Point Spreads & Betting Totals

The 2019 season will officially get underway on Thursday, September 5th. It’s the 100th anniversary season, so they decided to change things up.

In years past the defending champ would play at home in the opener. This season it’s a classic NFC North rivalry between the Green Bay Packers and Chicago Bears.

The New England Patriots will instead play their first games as defending champs on Sunday Night Football, as they are set to host the Pittsburgh Steelers.

The rest of Sunday’s card leaves a lot to be desired, as there’s just not a lot of great matchups on paper. There are a number of division games that will draw attention, but I would have to think Falcons @ Vikings, Chiefs @ Jaguars, Rams @ Panthers and [email protected] Browns are the best of the bunch.

Week 1 will conclude with a Monday Night Football double-header. First it will be the Texans @ Saints, followed by the Broncos @ Raiders.

Two teams are near double-digit favorites in Week 1. The Seahawks are 9.5-point home favorite of the Bengals and the eagles are 9.5-point home favorite against the Redskins.

For even more expert advice, be sure to check out our free NFL picks page.

Week 1 NFL Odds

Thursday, September 5, 2019

Time (TV)MatchupSpreadTotalPreview
8:30pm (NBC)Green Bay Packers
Chicago Bears
46.5 Preview

Sunday, September 08, 2019

Time (TV)MatchupSpreadTotalPreview
1:00pm (FOX)Atlanta Falcons
Minnesota Vikings
47.5 Preview
1:00pm (FOX)Washington Redskins
Philadelphia Eagles
46 Preview
1:00pm (CBS)Buffalo Bills
New York Jets
40 Preview
1:00pm (CBS)Baltimore Ravens
Miami Dolphins
37.5 Preview
1:00pm (CBS)Kansas City Chiefs
Jacksonville Jaguars
52 Preview
1:00pm (CBS)Tennessee Titans
Cleveland Browns
45.5 Preview
1:00pm (FOX)Los Angeles Rams
Carolina Panthers
50.5 Preview
4:05pm (CBS)Cincinnati Bengals
Seattle Seahawks
44 Preview
4:05pm (CBS)Indianapolis Colts
Los Angeles Chargers
43.5 Preview
4:25pm (FOX)Detroit Lions
Arizona Cardinals
47 Preview
4:25pm (FOX)San Francisco 49ers
Tampa Bay Buccaneers
50 Preview
4:25pm (FOX)New York Giants
Dallas Cowboys
45.5 Preview
8:20pm (NBC)Pittsburgh Steelers
New England Patriots
51 Preview

Monday, September 9, 2019

Time (TV)MatchupSpreadTotalPreview
7:10pm (ESPN)Houston Texans
New Orleans Saints
53.5 Preview
10:20pm (ESPN)Denver Broncos
Oakland Raiders
43 Preview

Check Out Each of the Weekly NFL Odds & Betting Lines: